Cytodiagnostics Maleimide-Activated Gold Nanoparticle Conjugation Kits have been optimized for high efficiency one-step conjugation of thiol-containing ligands such as oligonucleotides to gold nanoparticles.
The kits contains ready-to-use pre-made mixtures. No activation or manipulation of the gold nanoparticles is required prior to conjugation, which often results in poor performing conjugates. Simply mix your protein with the pre-activated maleimide gold nanoparticles supplied in the kit to generate your conjugate.
The precisely engineered gold surface coat on our maleimide-activated gold nanoparticles results in high conjugation efficiency and stable conjugates while minimizing non-specific binding in your assay.
Features & Benefits of Maleimide-Activated Gold Nanoparticles
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- Results in covalently bound ligand and more stable conjugate.
- Fast and convenient one-step conjugation reaction with no pre-activation requirements.
- Spacer between the gold nanoparticle surface and conjugated ligand minimizes effects on the tertiary protein structure, which can lead to poor performing conjugates, a common problem seen in conjugates prepared by passive adsorption.
- Precisely engineering surface coating that reduces non-specific protein binding in biological assays.